The Gold Standard in Skin Renewal

Anti-Acne & Anti-Wrinkle Treatments

Combat active breakouts and visible signs of aging simultaneously with South Africa’s most trusted retinoid range. Achieve smoother, firmer, and clearer skin with medical-grade formulas delivered in 2–4 days.
No prescription needed for online orders via our Store
No prescription needed for online orders via our Store
Verified Authentic
Verified Authentic
Secure Checkout
Secure Checkout
Delivery Partners:
Pep Store
Pep Store
SkyNet
SkyNet
The Courier Guy
The Courier Guy

Complete Anti-Aging & Acne Treatment Collection

Explore dermatologist-trusted products from tretinoins.co.za designed to target fine lines, wrinkles, and acne for clearer, younger-looking skin.

Combat acne and wrinkles simultaneously with our comprehensive range of prescription-strength retinoid treatments. Featuring tretinoin creams, gels, and complementary brightening agents, explore our full range of All Tretinoin Products for complete skin renewal.

  • Dual Benefits: Clear acne while reducing fine lines and wrinkles
  • Multiple Formulations: Creams and gels to suit your skin type
  • Various Strengths: From beginner 0.01% to advanced 0.1% concentrations
  • Clinically Proven: Backed by decades of dermatological research
  • Complete Solutions: Tretinoin, hydroquinone, and azelaic acid options — explore our Tretinoin Gels for lightweight formulas that absorb quickly and work effectively.

Transform your skin with scientifically proven treatments that address both acne and aging concerns. Perfect for anyone seeking clearer, smoother, younger-looking skin with our Tretinoin CreamsLearn more about safe use and retinoid guidance in our About Tretinoin section.

Explore by Skin Concern

Need guidance? Read our Tretinoin Buying Guide to choose the right strength and formula for your skin.